An adult and child have been taken to Ottawa hospitals after a collision on Cartwright Street at Victoria Street, just west of Russell.
Officials say one of the vehicles needed to have its roof cut off just before noon, in order to access three people inside.
One adult was rushed to The Ottawa Hospital's Civic Campus while a child was taken to the Children's Hospital of Eastern Ontario (CHEO).
There's been no word on the extent of their injuries.
Ottawa police say roads in the area remain closed for their investigation.